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  In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

  AbstractDespite scientific evidence originating from two patients published to date that CCR5Δ32/Δ32 hematopoietic stem cell transplantation (HSCT) can cure human immunodeficiency virus type 1 (HIV-1)

  2023-02-21

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  Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial

  AbstractImmune checkpoint inhibitors have shown efficacy against metastatic triple-negative breast cancer (mTNBC) but only for PD-L1positive disease. The randomized, placebo-controlled ALICE tria

  2022-12-09

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  A real-world comparison of tisagenlecleucel and axicabtagene ciloleucel CAR T cells in relapsed or refractory diffuse large B cell lymphoma

  AbstractAxicabtagene ciloleucel (axi-cel) and tisagenlecleucel (tisa-cel) have both demonstrated impressive clinical activity in relapsed/refractory (R/R) diffuse large B cell lymphoma (DLBCL). In thi

  2022-09-23

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  The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure: a multinational randomized trial

  AbstractThe sodium–glucose cotransporter 2 inhibitor empagliflozin reduces the risk of cardiovascular death or heart failure hospitalization in patients with chronic heart failure, but whether empagli

  2022-02-24

• Safety and target engagement of an oral small-molecule sequestrant in adolescents with autism spectrum disorder: an open-label phase 1b/2a trial

  AbstractAutism spectrum disorder (ASD) is defined by hallmark behaviors involving reduced communication and social interaction as well as repetitive activities and restricted interests. ASD represents

  2022-02-15

• Top Questions Answered About COVID Boosters for Your Patients

  Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center.Confusion continues to circulate in the wake of decisions on booster doses of the Pfize

  2021-09-24

• Back-to-School Viral Illnesses: 7 Classroom Contagions

  Image from the Centers for Disease Control and Prevention (CDC). [Public domain.]Are you ready for another school year? How different will 2021 look from 2020? Given the myriad issues over the past ye

  2021-08-23

• 6 Body Modifications: Dermatologic Risks and Adverse Reactions

  Image from Wikimedia Commons | Originalsinphoto.The ancient practice of body modification—including body piercing, skin implants, earlobe stretching, scarification (shown), tongue splitting, and

  2021-07-26