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  CRISPR gene-editing therapies for hypertrophic cardiomyopathy

  Pre-symptomatic gene editing in preclinical models of hypertrophic cardiomyopathy shows therapeutic promise; clinical studies are now needed to assess safety and efficacy in humans.The two groups use

  2023-02-18

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  Association of wearable device-measured vigorous intermittent lifestyle physical activity with mortality

  AbstractWearable devices can capture unexplored movement patterns such as brief bursts of vigorous intermittent lifestyle physical activity (VILPA) that is embedded into everyday life, rather than bei

  2022-12-29

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  Prospective evaluation of smartwatch-enabled detection of left ventricular dysfunction

  AbstractAlthough artificial intelligence (AI) algorithms have been shown to be capable of identifying cardiac dysfunction, defined as ejection fraction (EF) ≤ 40%, from 12-lead electrocardiograms (ECG

  2022-11-15

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  A digital mask to safeguard patient privacy

  AbstractThe storage of facial images in medical records poses privacy risks due to the sensitive nature of the personal biometric information that can be extracted from such images. To minimize these

  2022-09-16

• Machine learning model to predict mental health crises from electronic health records

  AbstractThe timely identification of patients who are at risk of a mental health crisis can lead to improved outcomes and to the mitigation of burdens and costs. However, the high prevalence of mental

  2022-05-16

• Robotic-Controlled, Fully Automated Capsule Endoscopy on Par With Conventional Method

  NEW YORK (Reuters Health) - Fully automated, magnetically controlled capsule endoscopy performs as well as conventional transoral gastroscopy for examining the stomach and small bowel, according to re

  2021-09-19

• Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system

  AbstractNon-alcoholic steatohepatitis (NASH) is a common form of chronic liver disease characterised by lipid accumulation, infiltration of immune cells, hepatocellular ballooning, collagen deposition

  2021-09-03

• Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase

  AbstractAlthough nanomaterials have shown promising biomedical application potential, incomplete understanding of their molecular interactions with biological systems prevents their inclusion into mai

  2021-08-13